Turn on Fluorescent Probes for Selective Targeting of Aldehydes
fluorescent probes; amine; fluorescence; imine; aldehyde; gaseous formaldehyde; rational design; reagents; sensors; system
Two different classes of fluorescent dyes were prepared as a turn off/on sensor system for aldehydes. Amino derivatives of a boron dipyrromethene (BDP) fluorophore and a xanthene-derived fluorophore (rosamine) were prepared. Model compounds of their product with an aldehyde were prepared using salicylaldehyde. Both amino boron dipyrromethene and rosamine derivatives are almost non-fluorescent in polar and apolar solvent. However, imine formation with salicylaldehyde on each fluorophore increases the fluorescence quantum yield by almost a factor of 10 (from 0.05 to 0.4). These fluorophores are therefore suitable candidates for development of fluorescence-based sensors for aldehydes.
Dilek, O., & Bane, S. L. (2016). Turn on Fluorescent Probes for Selective Targeting of Aldehydes. Chemosensors, 4(1), 5.
Dilek, Ozlem and Bane, Susan L., "Turn on Fluorescent Probes for Selective Targeting of Aldehydes" (2016). Chemistry Faculty Scholarship. 3.