Document Type
Dissertation
Date of Award
1974
Keywords
Organoselenium compounds
Degree Name
Doctor of Philosophy (PhD)
Department
Chemistry
First Advisor
Walter E. Kaskan
Second Advisor
Bruce E. Norcross
Third Advisor
Howard Alper
Abstract
The original purpose of this investigation was to prepare and isolate selenobiotin. Several attempts were made to prepare 3-(-carboxymethylseleno-)-alanine, a critical intermediate in the proposed synthetic sequence, without success. In view of this unexpected difficulty, the object of the research was changed to the synthesis of cis-3,4-ureyleneselenophane, the parent fused heterocyclic system. The formation of this molecule has been realized, and alternate pathways have been tested which establish a model system for the synthesis of selenobiotin.
Recommended Citation
Martin, Robert L., "Reactions directed towards the synthesis of selenobiotin" (1974). Graduate Dissertations and Theses. 230.
https://orb.binghamton.edu/dissertation_and_theses/230