Effects of Reduction in Social Enrichment on a Novel Rat Model of Approach and Avoidance Orientation
Publication Date
2024
Document Type
Book
Description
The goal of the present study was to evaluate the effects of a reduction in social enrichment by measuring behavioral changes in the Elevated Plus Maze (EPM) in male and female rats of High Approach (HAO) and Low Approach Orientation (LAO). The results indicated that at baseline, both total arm entries and open arm entries were affected by HAO vs LAO and sex. The percent change in closed arm entries in LAO females was sensitive to the social environment, whereas those in the HAO were behaviorally unaffected. The experimental LAO female group had an increase in percent change of closed arm entries while their control LAO counterparts had a decrease. Results suggest that the LAO female rats may translate to a population more sensitive to social stress and thus may be useful in identifying biological markers for predicting vulnerability to sudden changes in social environments.
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Recommended Citation
Feldman, Emily, "Effects of Reduction in Social Enrichment on a Novel Rat Model of Approach and Avoidance Orientation" (2024). Research Days Posters 2024. 8.
https://orb.binghamton.edu/research_days_posters_2024/8