Moving beyond the 2018 minimum international care considerations for osteoporosis management in duchenne muscular dystrophy (DMD): Meeting report from the 3rd International Muscle-Bone Interactions Meeting 7th and 14th November 2022

Authors

Kim Phung
Nicola Crabtree
Anne M. Connolly
Pat Furlong
Eric P. Hoffman, Binghamton University--SUNY
Stefan A. Jackowski
Soher Nagi Jayash
Alex Johnson
Khaldoun Koujok
Craig F. Munns
Erik Niks
Frank Rauch
Rachel Schrader
Cathy Turner
Elizabeth Vroom
David R. Weber
Brenda L. Wong
Michela Guglieri
Leanne M. Ward
Sze Choong Wong

Document Type

Article

Publication Date

11-16-2023

Keywords

Bisphosphonates; bone density; glucocorticoid; vertebral fracture

Abstract

This current manuscript summarizes the proceedings of the “Third Muscle-bone interactions in Duchenne Muscular Dystrophy Symposium: Moving Beyond the 2018 Minimum International Standards of Care for Osteoporosis Management”, an event co-organized by the World Duchenne Organization (www.worldduchenne.org) and the International Conference on Children’s Bone Health (www.theiscbh.org). This virtual symposium, held on November 7th and 14th 2022, brought together a total of 385 delegates representing 55 countries registered for the symposium, which included 239 clinicians, 70 researchers, 40 patient representatives and others from pharmaceutical companies and regulators. This symposium aimed to review the evidence base that informed the 2018 international minimum Care Considerations, best practices for implementation of these Care Considerations, and emerging knowledge that has arisen from research since the 2018 Care Considerations that shines light on the path forward. The online symposium and this report cover the following areas: 1. Current understanding of the bone morbidity in DMD, especially in relation to conventional glucocorticoid therapy. 2. The published, 2018 minimum international Care Considerations for osteoporosis monitoring and management in DMD. 3. Real world initiatives and challenges in the implementation of the 2018 minimum international Care Considerations for osteoporosis monitoring and management in DMD. 4. The need to consider strategies to move beyond the 2018 minimum international Care Considerations to prevent first fractures in DMD. 5. New therapies in DMD with potential impact on skeletal outcomes.

Comments

https://doi.org/10.3233/jnd-230176

Publisher Attribution

© 2023 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4.0).

Recommended Citation

Phung, Kim; Crabtree, Nicola; Connolly, Anne M.; Furlong, Pat; Hoffman, Eric P.; Jackowski, Stefan A.; Jayash, Soher Nagi; Johnson, Alex; Koujok, Khaldoun; Munns, Craig F.; Niks, Erik; Rauch, Frank; Schrader, Rachel; Turner, Cathy; Vroom, Elizabeth; Weber, David R.; Wong, Brenda L.; Guglieri, Michela; Ward, Leanne M.; and Wong, Sze Choong, "Moving beyond the 2018 minimum international care considerations for osteoporosis management in duchenne muscular dystrophy (DMD): Meeting report from the 3rd International Muscle-Bone Interactions Meeting 7th and 14th November 2022" (2023). Pharmacy Faculty Scholarship. 7.
https://orb.binghamton.edu/pharmacy_fac/7

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License