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Submissions from 2024

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Adrenal Suppression From Vamorolone and Prednisone in Duchenne Muscular Dystrophy: Results From the Phase 2b Clinical Trial, Alexandra Ahmet, Rebecca Tobin, Utkarsh J. Dang, Raoul Rooman, Michela Guglieri, Paula R. Clemens, Eric P. Hoffman, and Leanne M. Ward

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Assessment of Infant Exposure to Antidepressants through Breastfeeding: A Literature Review of Currently Available Approaches, Leah Arbitman, Shirley Chen, Brian Kim, Melinda Lee, Peng Zou, Bennett Doughty, Yanyan Li, and Tao Zhang

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The IAAM LTBP4 Haplotype is Protective Against Dystrophin-Deficient Cardiomyopathy, Luca Bello, Daniele Sabbatini, Aurora Fusto, Domenico Gorgoglione, Giovanni Umberto Borin, Martina Penzo, Pietro Riguzzi, Matteo Villa, Sara Vianello, Chiara Calore, Paola Melacini, Riccardo Vio, Andrea Barp, Grazia D’Angelo, Sandra Gandossini, Luisa Politano, Angela Berardinelli, Sonia Messina, Gian Luca Vita, Marina Pedemonte, Claudio Bruno, Emilio Albamonte, Valeria Sansone, Giovanni Baranello, Riccardo Masson, Guja Astrea, Adele D’Amico, Enrico Bertini, Marika Pane, Simona Lucibello, Eugenio Mercuri, Christopher Spurney, Paula Clemens, Lauren Morgenroth, Heather Gordish-Dressman, Craig M. McDonald, Eric P. Hoffman, CINRG-DNHS Investigators, and Elena Pegoraro

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Consensus recommendations for the use of novel antiretrovirals in persons with HIV who are heavily treatment-experienced and/or have multidrug-resistant HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy: An executive summary, David B. Cluck, Daniel B. Chastain, Milena Murray, Spencer H. Durham, Elias B. Chahine, Caroline Derrick, Julie B. Dumond, E. Kelly Hester, Sarah B. Jeter, Melissa D. Johnson, Christin Kilcrease, Wesley D. Kufel, Jeffrey Kwong, Amber F. Ladak, Nimish Patel, Sarah E. Pérez, Jonell B. Poe, Charlotte Bolch, Ian Thomas, Elizabeth Asiago-Reddy, and William R. Short

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Rivaroxaban Versus Apixaban: A Comparison Without a Simple Solution, Marc Cohen, Alex C. Spyropoulos, Shaun G. Goodman, Sarah A. Spinler, Marc. P. Bonaca, Theresa M. Redling, Gautam Visveswaran, and Sumit Sohal

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Efficacy and Safety of Vamorolone Over 48 Weeks in Boys With Duchenne Muscular Dystrophy: A Randomized Controlled Trial, Utkarsh J. Dang, Jesse M. Damsker, Michela Guglieri, Paula R. Clemens, Seth J. Perlman, Edward C. Smith, Iain Horrocks, Richard S. Finkel, Jean K. Mah, Nicolas Deconinck, Nathalie M. Goemans, Jana Haberlová, Volker Straub, Laurel Mengle-Gaw, Benjamin D. Schwartz, Amy Harper, Perry B. Shieh, Liesbeth De Waele, Diana Castro, Michele L. Yang, Monique M. Ryan, Craig M. McDonald, Mar Tulinius, Richard I. Webster, Hugh J. Mcmillan, Nancy Kuntz, Vamshi K. Rao, Giovanni Baranello, Stefan Spinty, Anne-Marie Childs, Annie M. Sbrocchi, Kathryn A. Selby, Migvis Monduy, Yoram Nevo, Juan J. Vilchez, Andres Nascimento-Osorio, Erik H. Niks, Imelda J M De Groot, Marina Katsalouli, John N. Van Den Anker, Leanne M. Ward, Mika Leinonen, Andrea L. D'Alessandro, and Eric P. Hoffman

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Pre-analytical challenges from adsorptive losses associated with thiamine analysis, Katie A. Edwards, Eileen A. Randall, Patricia C. Wolfe, Clifford E. Kraft, and Esther R. Angert

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Development of a Medication-Use Evaluation Template for Andexanet Alfa in the Reversal of Anticoagulation With Factor Xa Inhibitors, Toni Fera, Allison Burnett, Jessica Grandoni, Mary R. Moore, Barbara B. Nussbaum, Charles V. Pollack Jr., Anne E. Rose, Sarah A. Spinler, Michael B. Streiff, Charles J. Turck, and John Fanikos

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Diagnostic outcome of pro bono neurogenetic diagnostic service in Sri Lanka: A wealth creation, Lakmal Gonawala, Nalaka Wijekoon, Darshika Attanayake, Pyara Ratnayake, Darshana Sirisena, Harsha Gunasekara, Athula Dissanayake, Ajantha Keshavaraj, Chandra Mohan, W M. Steinbusch, Eric P. Hoffman, Ashwin Dalal, and K. Ranil D. de Silva

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Return of participant-level clinical trial results to participants: pilot of a simplified centralised approach, Eric Hoffman, Suzanne Gaglianone, Rahel Ketema, Wangshu Tu, Holly Peay, Paula Clemens, Utkarsh Dang, and Laurie Conklin

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Safety of enoxaparin in patients implanted with continuous flow left ventricular assist devices, Rachel C. Klosko, Bryan Whitson, Brent Lampert, Eric McLaughlin, and Libby Orzel

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Let's Have a Chat: How Well Does an Artificial Intelligence Chatbot Answer Clinical Infectious Diseases Pharmacotherapy Questions?, Wesley D. Kufel, Kathleen D. Hanrahan, Robert W. Seabury, Katie A. Parsels, Jason C. Gallagher, Conan MacDougall, Elizabeth W. Covington, Elias B. Chahine, Rachel S. Britt, and Jeffrey M. Steele

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A comprehensive survey of penicillin allergy education among United States Colleges and Schools of Pharmacy, Wesley D. Kufel, Meghan N. Jeffres, Christopher M. Bland, Bruce M. Jones, Mary L. Staicu, Julie Ann Justo, P. Brandon Bookstaver, and Lisa M. Avery

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A five-year quasi-experimental study to evaluate the impact of empiric antibiotic order sets on antibiotic use metrics among hospitalized adult patients, Wesley D. Kufel, Jeffrey M. Steele, Rahul Mahapatra, Mitchell V. Brodey, Dongliang Wang, Kristopher M. Paolino, Paul Suits, Derek W. Empey, and Stephen J. Thomas

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Graphene Oxide Nanosheets Toxicity in Mice Is Dependent on Protein Corona Composition and Host Immunity, Yue-ting Li, Kuo-Ching Mei, Revadee Liam-Or, Julie Tzu-Wen Wang, Farid N. Faruqu, Shengzhang Zhu, Yong-lin Wang, Yuan Lu, and Khuloud T. Al-Jamal

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Declining but Pronounced State-Level Disparities in Prescription Opioid Distribution in the United States, Joshua D. Madera, Amanda E. Ruffino, Adriana Felix, Kenneth L. McCall, Corey S. Davis, and Brian J. Piper

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Retrospective study investigating naloxone prescribing and cost in US Medicaid and Medicare patients, Christopher D. Manko, Mohamed S. Ahmed, Lavinia R. Harrison, Srivastava A. Kodavatiganti, Noelia Lugo, Jason Osei Konadu, Farrin Khan, Carrie A. Massari, Tenisha K. Sealey, Maame Efua Addison, Celine N. Mbah, Kenneth L. McCall, Joseph B. Fraiman, and Brian J. Piper

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Therapeutic failure reported with HIV long-acting injectables: An analysis of the FDA Adverse Event Reporting System from 2021 to 2024, Kenneth L. McCall, Danielle L. Cabral, Jamie F. Coghlan, Ashante M. Concepcion, Kristine E. Denimarck, and Shawn S. Shalumov

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Rising cases of drug-induced pulmonary fibrosis: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) database, 2000–2022, Kenneth L. McCall, Kelsey R. Hennig, Zachary T. Abe, Danielle N. Dattler, Karyssa L. Hurd, Sophie L. Portnoy, and Zoey J. Zagoria

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Qualitative evaluation to understand barriers and facilitators to prescribing angiotensin receptor-neprilysin inhibitors (ARNi) and sodium-glucose cotransporter inhibitors (SGLT2i) in patients with heart failure with reduced ejection fraction (HFrEF), Apoorva M. Pradhan, Mia E. Lussier, My Nguyen, Stephen J. Voyce, and Eric A. Wright

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Dalbavancin Sequential Therapy for Gram-Positive Bloodstream Infection: A Multicenter Observational Study, Nicholas Rebold, Sara Alosaimy, Jeffrey C. Pearson, Brandon Dionne, Ahmad Taqi, Abdalhamid Lagnf, Kristen Lucas, Mark Biagi, Nicholas Lombardo, Joshua Eudy, Daniel T. Anderson, Monica V. Mahoney, Wesley D. Kufel, Joseph A. D'Antonio, Bruce M. Jones, Jeremy J. Frens, Tyler Baumeister, Matthew Geriak, George Sakoulas, Dimitrios Farmakiotis, Dino Delaportas, Jeremy Larew, Michael P. Veve, and Michael J. Rybak

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A population-based study of children suggests blunted morning cortisol rhythms are associated with alterations of the systemic inflammatory state, Runia Roy, Utkarsh J. Dang, Kim M. Huffman, Tchilabalo Alayi, Yetrib Hathout, Kanneboyina Nagaraju, Paul S. Visich, and Eric P. Hoffman

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High mobility group box 1 (HMGB1) is a potential disease biomarker in cell and mouse models of Duchenne muscular dystrophy, Rebecca A. Slick, Jessica Sutton, Margaret Haberman, Benjamin S. O'Briens, Jennifer A. Tinklenberg, Aashay Mardikar, Mariah J. Prom, Margaret Beatka, Melanie Gartz, Mark A. Vanden Avond, Emily Siebers, David L. Mack, J. Patrick Gonzalez, Allison D. Ebert, Kanneboyina Nagaraju, and Michael W. Lawlor

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State-level variation in distribution of oxycodone and opioid-related deaths from 2000 to 2021: an ecological study of ARCOS and CDC WONDER data in the USA, Jay P. Solgama, Edward Liu, Mellar Davis, Jove Graham, Kenneth L. McCall, and Brian J. Piper

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Dynamic Changes in the Distribution of Hydrocodone and Oxycodone in Florida from 2006 to 2021, Elena Lynn Stains, Akshay C. Patel, Jay P. Solgama, Joseph D. Hagedorn, Kenneth L. McCall, and Brian J. Piper

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Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling, Nydia Tejeda-Muñoz, Yagmur Azbazdar, Eric A. Sosa, Julia Monka, Pu-Sheng Wei, Grace Binder, Kuo-Ching Mei, Yerbol Z. Kurmangaliyev, and Edward M. De Robertis

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Emerging therapeutic strategies for Wnt-dependent colon cancer targeting macropinocytosis, Nydia Tejeda-Munoz, Grace Binder, and Kuo-Ching Mei

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Wnt signaling in cell adhesion, development, and colon cancer, Nydia Tejeda-Muñoz and Kuo-Ching Mei

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Combinatorial Anti-Cancer Effect of Polypurine Reverse Hoogsteen Hairpins against KRAS and MYC Targeting in Prostate and Pancreatic Cancer Cell Lines, Simonas Valiuska, Kayla K. Elder, Steven J. McKay, Carlos J. Ciudad, Véronique Noé, and Tracy A. Brooks

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The RNA-binding protein Msi2 regulates autophagy during myogenic differentiation, Ruochong Wang, Futaba Kato, Rio Yasui Watson, Aaron M. Beedle, Jarrod A. Call, Yugo Tsunoda, Takeshi Noda, Takaho Tsuchiya, Makoto Kashima, Ayuna Hattori, and Takahiro Ito

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Enhancing RNA-lipid nanoparticle delivery: Organ- and cell-specificity and barcoding strategies, Pu-Sheng Wei, Nagasri Thota, Greshma John, Evelyn Chang, Sunjae Lee, Yuanjun Wang, Zitao Ma, Yu-Hsuan Tsai, and Kuo-Ching Mei

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Title-molecular diagnostics of dystrophinopathies in Sri Lanka towards phenotype predictions: an insight from a South Asian resource limited setting, Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Roshan Liyanage, Dhammika Amaratunga, Yetrib Hathout, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman, and K. Ranil D. de Silva

Submissions from 2023

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Inflammatory Biomarkers Associated with Brain MRI Measures: Framingham Heart Study Offspring Cohort, Jiachen Chen, Margaret Doyle, Yuan Fang, Ahmed A. Y. Ragab, Joanne Murabito, and Kathryn Lunetta

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Efficacy and Safety of Viltolarsen in Boys With Duchenne Muscular Dystrophy: Results From the Phase 2, Open-Label, 4-Year Extension Study, Paula R. Clemens, Vamishi K. Rao, Anne M. Connolly, Amy D. Harper, Jean K. Mah, Craig M. McDonald, Edward C. Smith, Craig M. Zaidman, Tomoyuki Nakagawa, the CINRG DNHS Investigators ., and Eric P. Hoffman

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An Analysis of Oxycodone and Hydrocodone Distribution Trends in Delaware, Maryland, and Virginia Between 2006 and 2014, Conor M. Eufemio, Joseph D. Hagedorn, Kenneth L. McCall, and Brian J. Piper

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Clustering microbiome data using mixtures of logistic normal multinomial models, Yuan Fang and Sanjeena Subedi

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A fleeting glimpse of functional benefit of the complete DMD gene in a large animal model of Duchenne muscular dystrophy, Eric P. Hoffman

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Early life exposure to broccoli sprouts confers stronger protection against enterocolitis development in an immunological mouse model of inflammatory bowel disease, Lola Holcomb, Johanna M. Holman, Molly Hurd, Brigitte Lavoie, Louisa Colucci, Benjamin Hunt, Timothy Hunt, Marissa Kinney, Jahnavi Pathak, Gary M. Mawe, Peter L. Moses, Emma Perry, Allesandra Stratigakis, Tao Zhang, Grace Chen, Suzanne L. Ishaq, and Yanyan Li

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Steamed broccoli sprouts alleviate DSS-induced inflammation and retain gut microbial biogeography in mice, Johanna M. Holman, Louisa Colucci, Dorien Baudewyns, Joe Balkan, Timothy Hunt, Benjamin Hunt, Marissa Kinney, Lola Holcomb, Allesandra Stratigakis, Grace Chen, Peter L. Moses, Gary M. Mawe, Tao Zhang, Yanyan Li, and Suzanne L. Ishaq

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Toxoplasma membrane inositol phospholipid binding protein TgREMIND is essential for secretory organelle function and host infection, Rodrigue Houngue, Lamba Omar Sangaré, Tchilabalo Dilezitoko Alayi, Aissatou Dieng, Tristan Bitard-Feildel, Claire Boulogne, Christian Slomianny, Cynthia Menonve Atindehou, Lucie Ayi Fanou, Yetrib Hathout, Isabelle Callebaut, and Stanislas Tomavo

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An analysis of patterns of distribution of buprenorphine in the United States using ARCOS, Medicaid, and Medicare databases, Zhi-Shan Hsu, Justina A. Warnick, Tice R. Harkins, Briana E. Sylvester, Neal K. Bharati, leTausjua B. Eley, Stephanie D. Nichols, Kenneth McCall, and Brian J. Piper

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Dynamic changes in methadone utilisation for opioid use disorder treatment: a retrospective observational study during the COVID-19 pandemic, Amy L. Kennalley, Jessica L. Fanelli, John A. Furst, Nicholas J. Mynarski, Margaret A. Jarvis, Stephanie D. Nicholas, Kenneth L. McCall, and Brian J. Piper

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Pronounced state-level disparities in prescription of cannabinoids to medicaid patients, Edward Y. Liu, Kenneth L. McCall, and Brian J. Piper

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MMP-2 regulates Src activation via repression of the CHK/MATK tumor suppressor in osteosarcoma, Deanna V. Maybee, Christopher R. Cromwell, Basil P. Hubbard, and Mohammad A.M. Ali

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Moving beyond the 2018 minimum international care considerations for osteoporosis management in duchenne muscular dystrophy (DMD): Meeting report from the 3rd International Muscle-Bone Interactions Meeting 7th and 14th November 2022, Kim Phung, Nicola Crabtree, Anne M. Connolly, Pat Furlong, Eric P. Hoffman, Stefan A. Jackowski, Soher Nagi Jayash, Alex Johnson, Khaldoun Koujok, Craig F. Munns, Erik Niks, Frank Rauch, Rachel Schrader, Cathy Turner, Elizabeth Vroom, David R. Weber, Brenda L. Wong, Michela Guglieri, Leanne M. Ward, and Sze Choong Wong

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Duchenne muscular dystrophy from brain to muscle: The role of brain dystrophin isoforms in motor functions, Nalaka Wijekoon, Lakmal Gonawala, Pyara Ratnayake, Dhammika Amaratunga, Yetrib Hathout, Chandra Mohan, Harry W. M. Steinbusch, Ashwin Dalal, Eric P. Hoffman, and K. Ranil D. de Silva

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Understanding and mitigating thiaminase activity in silver carp, Patricia C. Wolfe, Amber M. Tuske, Donald E. Tillitt, Fred Allen, and Katie A. Edwards

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Visualizing drug-induced lipid accumulation in lysosomes of live cancer cells with stimulated Raman imaging, Yuhao Yuan, Emmanuel O. Olawode, L. Nathan Tumey, and Fake Lu