Publication Date
2024
Document Type
Book
Description
Tissue engineering aims to address organ failure through engineered tissues. My research focuses on creating biomimetic scaffolds with ideal biomechanical properties and biocompatibility, utilizing 3D printing, bioprinting, electrospinning and molding. We electrospun microtubes with over 5 um in diameter to mimic capillary vessels, which provides topography for cell attachment, growth, proliferation, and vascularization. Combining scissored microtubes with hydrogels, composite scaffolds can be bioprinted with improved scaffold strength and cell viability. To reduce cell damage during bioprinting, slow-gelling material was introduced and molded into 3D-printed sacrificial molds to fabricate hydrogel scaffolds. Future steps involve integrating electrospun microtubes with slow-gelled hydrogel scaffolds to create multiscale structures. This research contributes to evolving tissue engineering, offering potential solutions to the organ shortage.
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Recommended Citation
Chen, Yan and Zhou, Yingge, "Multiscale Channelized Biomimetic Scaffolds for Tissue Vascularization" (2024). Research Days Posters 2024. 3.
https://orb.binghamton.edu/research_days_posters_2024/3